Do not store the pen with the needle attached to prevent leaking, blocking the needle, and air. Dont drink alcohol or use other medicines that contain alcohol. Humulin r u500 prescribing informationlinr5000005uspi. Before using solostar, the instructions for use included in the package leaflet must be read carefully.
See full prescribing information for important administration instructions 2. Long acting insulin toujeo insulin glargine injection. The mean baselinecorrected serum calcium for the aredia 60mg and etidronate disodium groups were. Apidra solostar unitsml solution for injection in a prefilled pen. Never share an apidra solostar pen between patients, even if the needle is changed. Early introduction of insulin therapy can attain and maintain glucose targets when oral antidiabetic drug oad regimens have failed to achieve glycemic goals, thereby reducing the risk. Apidra insulin glulisine injection, for subcutaneous or. Millions of people every day count on lantus to help them manage their a1c and control their blood sugar. Toujeo has been studied versus lantus insulin glargine injection 100 unitsml in four pivotal clinical trials the edition study program involving more than 3000 patients and in two euglycemic clamp studies to assess pharmacokinetics pk and pharmacodynamics pd. Rotateinfusion sites within the same region to reduce the risk of. Inject the dose by pressing the pushbutton all the way in until the 0 lines up with the pointer see diagram i. Moderate patients with diabetes mellitus should be monitored apidra package insert during somatropin recombinant rhgh jnsert.
Aspart novolog 5 15 min 30 90 min lispro humalog, admelog apidra short acting regular 30 60 min 2 3 hrs 5 8 hrs basal intermediate nph 2 4 hrs 4 10 hrs 10 16 hrs long acting detemir levemir 3 8 hrs no peak 6 24 hrs glargine lantus basaglar 2 4 hrs 20 24 hrs. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is the leaflet included in the pack chris may field menu. This information is not intended to be used as a tool to prescribe medication or provide other clinical services. Limitations of use 5not recommended for the treatment of diabetic ketoacidosis. Apidra insulin glulisine rdna origin injection solution for injection. More severe episodes with coma, seizure, or neurologic impairment may be treated with intramuscular subcutaneous glucagon or. Enbrel etanerceptinjection, for subcutaneous use enbrel etanercept for injection, for subcutaneous use initial u. Apidra insulin glulisine injection rdna origin is a recombinant human insulin analogue indicated for. Videos demonstrating insertion and removal are available online for trained healthcare providers. Important safety information for apidra insulin glulisine injection 100 unitsml. Apidra, inninsulin glulisine european medicines agency. Has the participant had an adverse reaction to or would be reasonably expected to have an adverse reaction to a majority two or more in a class with at least two alternatives or one in a. Moderate monitor blood glucose levels regularly in patients with diabetes, apidra package insert when lanreotide treatment is initiated or when the dose is altered. The safety of novolog was evaluated in two treattotarget trials of 6 months duration, conducted in subjects with type 1 diabetes or type 2 diabetes see clinical studies 14.
Highlights of prescribing information these highlights do not include all the information needed to use humulinnsafely and effectively. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is. Lantus can be refrigerated until the expiration date. With apidra mealtime insulin, you can help manage your blood sugar at mealtime. Call the merck national service center at 18778884231 if you have any questions. Apidra solostar 100 unitsml solution for injection in a prefilled pen. Inject subcutaneously into the thigh, upper arm, or abdomen 2. Pharmacist and physician resources and faqs toujeo. Humulinn isophane insulinhumansuspension, for subcutaneous use initial u. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is the leaflet included in the pack with a.
Apidra is indicated to improve glycemic control in adults and children with diabetes mellitus. The united kingdom prospective diabetes study demonstrated the progressive decline in. Deplin tablets folic acid, when administered in daily doses above 800 mcg, may increase the amount of unmetabolized folic description less likely than folic acid to accelerate the growth of existing neoplasms. Apidra insulin glulisine injection rdna origin is a recombinant. Aug 22, 2019 apidra solostar unitsml solution for injection in a prefilled pen.
Alternatively, you can report any side effects of prescription drugs directly to the fda. The apidra solostar prefilled pen dials in 1unit increments. Unscrew the capped needle and throw it away see disposing of pens and needlessection below. In order to monitor the safety of astrazeneca products, we encourage reporting any side effects experienced while taking an astrazeneca product to the az information center at 18002369933. Apidra should be given by subcutaneous injection shortly 015 min before or soon after meals or by. Humulin r insulin human injection is a shortacting human insulin for subcutaneous or intravenous use. Hyperglycemia or hypoglycemia with changes in insulin regimen. Highlights of prescribing information these highlights. Do not mix apidra for subcutaneous injection with insulin preparations other than nph insulin. If apidra is mixed with nph insulin, draw apidra into the syringe first and inject immediately after mixing. When given subcutaneously, apidra has a more rapid onset of action and a shorter duration of action than regular human insulin. Novolog, humalog, and apidra are compatible with the omnipod system for use up to 72 hours 3 days.
The use of afrezza is not recommended in patients who smoke or who have recently stopped smoking. Nov 15, 2019 provides trustworthy package insert and label information about marketed drugs as submitted by manufacturers to the us food and drug administration. Apidra given 2 minutes apidra pre before the start of a meal compared to regular human insulin given 30 minutes regular 30 min before start of the meal see figure 1a and compared to regular human insulin regular pre given 2 minutes before a meal see figure 1b. Apidra is not compatible with dextrose solution and ringers solution. Aug 31, 2018 moderate green tea catechins have been apidra package insert to decrease serum glucose concentrations. Highlights of prescribing information hyperglycemia or. Guide for storage of insulin wisconsin department of. Highlights of prescribing information these highlights do. Highlights of prescribing information these highlights do not include all the information needed to use humalog safely and effectively. How to use apidra solostar pen apidra insulin glulisine. Always use a new sterile needle for each injection. Apidra insulin glulisine injection, solution apidra.
How to use your lantus solostar pen what is lantus. Apidra is a recombinant insulin analog that is equipotent to human insulin i. Apidra, humulin excluding u 500, humalog medical necessity prior authorization form confidential page 2 of 2 revised. Fda approves admelog, the first shortacting followon insulin product to treat diabetes. The afrezza inhaler can be used for up to 15 days from the date of. Solostar, the instructions for use included in the package leaflet must be read carefully.
If a foil package, blister card or strip is not refrigerated, the contents must be used within 10 days. Apidra dosing apidra insulin glulisine injection 100 unitsml. Dailymed apidra insulin glulisine injection, solution. Guide for storage of insulin every effort is made to assure the accuracy of the attached information. Highlights of prescribing information these highlights do not. When used in an external insulin pump for subcutaneous infusion, apidra should not be mixed. Administer humalog u100 by continuous subcutaneous infusion in a region recommended in the instructions from the pump manufacturer. The safety and efficacy of afrezza in patients who smoke has not been established. Click here for full prescribing information for apidra. Any reference in these archives to astrazeneca products or their uses may not reflect current medical knowledge and should not be used as a source of information on the present product label, efficacy data or safety data. Aug 10, 2019 apidra solostar unitsml solution for injection in a prefilled pen. Afrezza in patients with chronic lung disease has not been established. Aspart novolog 5 15 min 30 90 min lispro humalog admelog apidra short acting regular 30 60 min 2 3 hrs 5 8 hrs basal intermediate nph 2 4 hrs 4 10 hrs 10 16 hrs long acting detemir levemir 3 8 hrs no peak 6 24 hrs glargine lantus basaglar 2. Administer only under medical supervision after diluting to concentrations from 0.
Jakafi is indicated for treatment of intermediate or highrisk myelofibrosis mf, including primary mf, postpolycythemia vera mf and postessential thrombocythemia mf in adults. Mar 17, 2020 apidra solostar unitsml solution for injection in a prefilled pen. Continuous subcutaneous insulin infusion csii in pump. What information is on the taxol paclitaxel package insert. Moderate green tea catechins have been apidra package insert to decrease serum glucose concentrations. Glucose monitoring is essential for patients receiving insulin therapy. Apidra insulin glulisine injection rdna origin is a recombinant human insulin. Follow closely the instructions for dose, monitoring blood tests, diet and physical activity physical work and exercise as discussed with your. If apidra is mixed with nph insulin, draw apidra into the syringe first and inject immediately after. The most common side effect of any insulin, including toujeo, is low blood sugar hypoglycemia, which may be serious and lifethreatening. Your health professional has decided that solostar is appropriate for you, based on your ability to handle solostar. Humulin r is produced by recombinant dna technology utilizing a nonpathogenic laboratory strain of escherichia coli.
Lantus insulin glargine 100 unitsml is the most prescribed long acting insulin. Apidra insulin glulisine injection, for subcutaneous or intravenous use. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and. Apidra is approved to be taken within 15 minutes before or within 20 minutes after starting a meal. Before using solostar, the instructions for use included in the package leaflet must be. Highlights of prescribing information these highlights do not include all the information needed to use enbrel safely and effectively. Highlights of prescribing information administration. If you are unsure of the necessary steps to safely insert andor remove nexplanon, do not attempt the procedure. Before using a different insulin with the omnipod system, check the insulin drug label to make sure it can be used with a pump. Apidra package insert pdf in turn, under these presuppositions the contractor does not assume liability that, for disturbances specified vorlagd bids that without disturbances would have led to a conclusion of contract, can only be submitted incomplete or with delay. It has a dark blue injection buttonwith a raised ring on the top. Apidra is stable at room temperature for 48 hours only in normal saline solution 0. Every individual package label entry contains a unique identifier which can.
Do not use apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in apidra. Patient and family education regarding hypoglycemia management is apidra package insert the patient and patients family should be instructed on how to recognize packsge manage the symptoms of hypoglycemia. Apidra may be infused subcutaneously by external insulin infusion pumps. Thirty patients were randomized to receive aredia and 35 to receive etidronate disodium. Highlights of prescribing information nexplanon safely and. While using toujeo, do not drive or operate heavy machinery until you know how toujeo affects you. Information for the user apidra solostar 100 unitsml solution for injection in a prefilled pen insulin glulisine talk to your doctor, pharmacist or nurse before using apidra. All studies in the edition clinical program were 26week, openlabel, controlled, titratetotarget, noninferiority. Adjustments in drug dosage, meal patterns, or exercise may be needed. After 15 days of use, the inhaler must be discarded and replaced with a new inhaler. Nov 15, 2019 never share needles or syringes with another person. Dec 06, 2019 never share an apidra solostar pen between patients, even if the needle is changed.
Dailymed humulin r insulin human injection, solution. Mild episodes of hypoglycemia usually can be treated with oral glucose. Highlights of prescribing information these highlights do not include all the information needed to use toujeo safely and effectively. Novolog is available in the following package sizes.
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