When used in an external insulin pump for subcutaneous infusion, apidra should not be mixed. Your health professional has decided that solostar is appropriate for you, based on your ability to handle solostar. Call the merck national service center at 18778884231 if you have any questions. Long acting insulin toujeo insulin glargine injection. Highlights of prescribing information hyperglycemia or. Humulin r u500 prescribing informationlinr5000005uspi. Administer only under medical supervision after diluting to concentrations from 0. Humulinn isophane insulinhumansuspension, for subcutaneous use initial u. Apidra insulin glulisine injection, for subcutaneous or intravenous use. Pharmacist and physician resources and faqs toujeo. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is the leaflet included in the pack chris may field menu. Apidra may be infused subcutaneously by external insulin infusion pumps. Apidra insulin glulisine injection, for subcutaneous or. Highlights of prescribing information these highlights do not include all the information needed to use humalog safely and effectively.
Glucose monitoring is essential for patients receiving insulin therapy. It has a dark blue injection buttonwith a raised ring on the top. Never share an apidra solostar pen between patients, even if the needle is changed. Apidra is indicated to improve glycemic control in adults and children with diabetes mellitus. Humulin r insulin human injection is a shortacting human insulin for subcutaneous or intravenous use. Lantus can be refrigerated until the expiration date. The most common side effect of any insulin, including toujeo, is low blood sugar hypoglycemia, which may be serious and lifethreatening. Dailymed humulin r insulin human injection, solution. Mar 17, 2020 apidra solostar unitsml solution for injection in a prefilled pen. Millions of people every day count on lantus to help them manage their a1c and control their blood sugar.
Prescription lantus is a longacting insulin used to treat adults with type 2 diabetes and adults and pediatric patients children 6 years and older with type 1 diabetes for the control of high blood sugar. Aug 10, 2019 apidra solostar unitsml solution for injection in a prefilled pen. Aug 22, 2019 apidra solostar unitsml solution for injection in a prefilled pen. Do not store the pen with the needle attached to prevent leaking, blocking the needle, and air.
Highlights of prescribing information these highlights do not include all the information needed to use enbrel safely and effectively. Nov 15, 2019 never share needles or syringes with another person. Apidra insulin glulisine rdna origin injection solution for injection. See full prescribing information for important administration instructions 2.
While using toujeo, do not drive or operate heavy machinery until you know how toujeo affects you. All studies in the edition clinical program were 26week, openlabel, controlled, titratetotarget, noninferiority. Apidra should be given by subcutaneous injection shortly 015 min before or soon after meals or by. Has the participant had an adverse reaction to or would be reasonably expected to have an adverse reaction to a majority two or more in a class with at least two alternatives or one in a. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and.
Important notice for users you are about to access astrazeneca historic archive material. The safety and efficacy of afrezza in patients who smoke has not been established. The afrezza inhaler can be used for up to 15 days from the date of. Aspart novolog 5 15 min 30 90 min lispro humalog, admelog apidra short acting regular 30 60 min 2 3 hrs 5 8 hrs basal intermediate nph 2 4 hrs 4 10 hrs 10 16 hrs long acting detemir levemir 3 8 hrs no peak 6 24 hrs glargine lantus basaglar 2 4 hrs 20 24 hrs. Dailymed apidra insulin glulisine injection, solution. The mean baselinecorrected serum calcium for the aredia 60mg and etidronate disodium groups were. Humulin r is produced by recombinant dna technology utilizing a nonpathogenic laboratory strain of escherichia coli.
Highlights of prescribing information thiazolidinediones. Always use a new sterile needle for each injection. Aug 31, 2018 moderate green tea catechins have been apidra package insert to decrease serum glucose concentrations. Moderate patients with diabetes mellitus should be monitored apidra package insert during somatropin recombinant rhgh jnsert. Rotate injection sites to reduce risk of lipodystrophy and localized cutaneous amyloidosis 2. Highlights of prescribing information these highlights do not include all the information needed to use toujeo safely and effectively. Lantus insulin glargine 100 unitsml is the most prescribed long acting insulin. Enbrel etanerceptinjection, for subcutaneous use enbrel etanercept for injection, for subcutaneous use initial u. Apidra is a recombinant insulin analog that is equipotent to human insulin i.
Mild episodes of hypoglycemia usually can be treated with oral glucose. Highlights of prescribing information these highlights do. Moderate green tea catechins have been apidra package insert to decrease serum glucose concentrations. Rotateinfusion sites within the same region to reduce the risk of. More severe episodes with coma, seizure, or neurologic impairment may be treated with intramuscular subcutaneous glucagon or. Thirty patients were randomized to receive aredia and 35 to receive etidronate disodium. Jakafi is indicated for treatment of intermediate or highrisk myelofibrosis mf, including primary mf, postpolycythemia vera mf and postessential thrombocythemia mf in adults. Do not mix apidra for subcutaneous injection with insulin preparations other than nph insulin. Apidra dosing apidra insulin glulisine injection 100 unitsml. If you are unsure of the necessary steps to safely insert andor remove nexplanon, do not attempt the procedure. Dont drink alcohol or use other medicines that contain alcohol.
The data in table 1 reflect the exposure of 596 patients with type 1 diabetes to novolog in one clinical trial with a mean exposure duration to novolog of 24. Apidra, inninsulin glulisine european medicines agency. Novolog is available in the following package sizes. Important safety information for apidra insulin glulisine injection 100 unitsml. Apidra solostar 100 unitsml solution for injection in a prefilled pen. Apidra is approved to be taken within 15 minutes before or within 20 minutes after starting a meal. Apidra is stable at room temperature for 48 hours only in normal saline solution 0. Hyperglycemia or hypoglycemia with changes in insulin regimen. The apidra solostar prefilled pen dials in 1unit increments.
Information for the user apidra solostar 100 unitsml solution for injection in a prefilled pen insulin glulisine talk to your doctor, pharmacist or nurse before using apidra. Highlights of prescribing information these highlights. Highlights of prescribing information these highlights do not. Alternatively, you can report any side effects of prescription drugs directly to the fda.
Every individual package label entry contains a unique identifier which can. Apidra insulin glulisine injection rdna origin is a recombinant human insulin analogue indicated for. Fda approves admelog, the first shortacting followon insulin product to treat diabetes. Novolog, humalog, and apidra are compatible with the omnipod system for use up to 72 hours 3 days. Early introduction of insulin therapy can attain and maintain glucose targets when oral antidiabetic drug oad regimens have failed to achieve glycemic goals, thereby reducing the risk. This information is not intended to be used as a tool to prescribe medication or provide other clinical services. Apidra package insert pdf in turn, under these presuppositions the contractor does not assume liability that, for disturbances specified vorlagd bids that without disturbances would have led to a conclusion of contract, can only be submitted incomplete or with delay. Inject subcutaneously into the thigh, upper arm, or abdomen 2. The united kingdom prospective diabetes study demonstrated the progressive decline in. Do not use this solostarif the insulin is cloudy, colored or has particles. The safety of novolog was evaluated in two treattotarget trials of 6 months duration, conducted in subjects with type 1 diabetes or type 2 diabetes see clinical studies 14.
Solostar, the instructions for use included in the package leaflet must be read carefully. Inject the dose by pressing the pushbutton all the way in until the 0 lines up with the pointer see diagram i. Apidra solostar unitsml solution for injection in a prefilled pen. The use of afrezza is not recommended in patients who smoke or who have recently stopped smoking. Continuous subcutaneous insulin infusion csii in pump. What information is on the taxol paclitaxel package insert. Dec 06, 2019 never share an apidra solostar pen between patients, even if the needle is changed. Click here for full prescribing information for apidra. If a foil package, blister card or strip is not refrigerated, the contents must be used within 10 days. After 15 days of use, the inhaler must be discarded and replaced with a new inhaler. If apidra is mixed with nph insulin, draw apidra into the syringe first and inject immediately after mixing. Apidra is not compatible with dextrose solution and ringers solution.
Adjustments in drug dosage, meal patterns, or exercise may be needed. Follow closely the instructions for dose, monitoring blood tests, diet and physical activity physical work and exercise as discussed with your. Before using solostar, the instructions for use included in the package leaflet must be. Apidra insulin glulisine injection, solution apidra. Apidra given 2 minutes apidra pre before the start of a meal compared to regular human insulin given 30 minutes regular 30 min before start of the meal see figure 1a and compared to regular human insulin regular pre given 2 minutes before a meal see figure 1b. Guide for storage of insulin every effort is made to assure the accuracy of the attached information. Toujeo has been studied versus lantus insulin glargine injection 100 unitsml in four pivotal clinical trials the edition study program involving more than 3000 patients and in two euglycemic clamp studies to assess pharmacokinetics pk and pharmacodynamics pd. Administer humalog u100 by continuous subcutaneous infusion in a region recommended in the instructions from the pump manufacturer. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is. Do not use apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in apidra. How to use your lantus solostar pen what is lantus. Apidra insulin glulisine injection rdna origin is a recombinant. Guide for storage of insulin wisconsin department of. If apidra is mixed with nph insulin, draw apidra into the syringe first and inject immediately after.
Unscrew the capped needle and throw it away see disposing of pens and needlessection below. When given subcutaneously, apidra has a more rapid onset of action and a shorter duration of action than regular human insulin. Highlights of prescribing information nexplanon safely and. How to use apidra solostar pen apidra insulin glulisine. Apidra, humulin excluding u 500, humalog medical necessity prior authorization form confidential page 2 of 2 revised. In order to monitor the safety of astrazeneca products, we encourage reporting any side effects experienced while taking an astrazeneca product to the az information center at 18002369933. Patient and family education regarding hypoglycemia management is apidra package insert the patient and patients family should be instructed on how to recognize packsge manage the symptoms of hypoglycemia. Aspart novolog 5 15 min 30 90 min lispro humalog admelog apidra short acting regular 30 60 min 2 3 hrs 5 8 hrs basal intermediate nph 2 4 hrs 4 10 hrs 10 16 hrs long acting detemir levemir 3 8 hrs no peak 6 24 hrs glargine lantus basaglar 2. Highlights of prescribing information these highlights do not include all the information needed to use humulinnsafely and effectively. Nov 15, 2019 provides trustworthy package insert and label information about marketed drugs as submitted by manufacturers to the us food and drug administration. Afrezza in patients with chronic lung disease has not been established. With apidra mealtime insulin, you can help manage your blood sugar at mealtime.
Highlights of prescribing information administration. This information is intended as a tool for oqa surveyors to assist in evaluating medication therapy only. Before using solostar, the instructions for use included in the package leaflet must be read carefully. Any reference in these archives to astrazeneca products or their uses may not reflect current medical knowledge and should not be used as a source of information on the present product label, efficacy data or safety data. Before using a different insulin with the omnipod system, check the insulin drug label to make sure it can be used with a pump. Deplin tablets folic acid, when administered in daily doses above 800 mcg, may increase the amount of unmetabolized folic description less likely than folic acid to accelerate the growth of existing neoplasms. Videos demonstrating insertion and removal are available online for trained healthcare providers. Apidra insulin glulisine injection rdna origin is a recombinant human insulin. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is the leaflet included in the pack with a. Moderate monitor blood glucose levels regularly in patients with diabetes, apidra package insert when lanreotide treatment is initiated or when the dose is altered. Limitations of use 5not recommended for the treatment of diabetic ketoacidosis.
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